On May 22, 2020, the U.S. Food and Drug Administration approved Phexxi, making it the first non-hormonal, on-demand contraceptive that regulates vaginal pH levels. Phexxi is manufactured by Evofem Biosciences, located in San Diego. According to Phexxi’s official website, Evofem Biosciences is devoted to developing innovative healthcare solutions that put women “in control of [their] sexual and reproductive health."